Juutilainen J, Naarala J (2007).
fibroblasts, rat C6 glioblastoma cells, human SH-SY5Y neuroblastoma
cells and rat primary astrocytes were exposed to RFR at 872 MHz.
The cells were exposed for 2,8, or 24 hours to continuous wave
(CW) RFR or to a GSM type signal pulse modulated at 217 Hz, at
SARs of 1.5, 2.5, or 6.0 W/kg (except in the case of the primary
astrocytes, which were not exposed at 2.5 W/kg). Cellular ODC
levels were determined.
was reduced in primary astrocytes at a statistically significant
level, at both 1.5 and 6.0 W/kg SAR, and in both CW and GSM modulated
exposure. In the secondary cell lines ODC activity was generally
unaffected, except in two instances that may have been related
to accidental temperature increase in the cell medium.
point out that decrease in ODC activity leads to impaired polyamine
synthesis, which results in decreased proliferation.