Diem E, Schwarz C, Adlkofer F, Jahn O, et al. (2005)

Diem and colleagues in this study attempted to examine whether exposure to RFR at cell phone frequencies and power could damage DNA. They exposed human fibroblast cells and rat tumour cells in a double-blind study, to RFR at 1800 MHz at maximum SARs of 2 W/kg for up to 24 hours. Four different exposures were employed. These were continuous, intermittent (5 minutes on and 10 minutes off), pulse-modulation intermittent (5 minutes on and 10 minutes off), and talk-modulation continuous. Each was compared with a sham exposure. Temperature was controlled throughout the experiment. The effect on DNA was examined using the alkaline and neutral comet assays.

The results were assessed at 4, 16, and 24 hours of exposure. Statistically significant differences between sham and RFR exposure were seen at 16 and 24 hours in both cell types and in all varieties of exposure. In human cells, the alkaline comet assay showed significantly higher effects in the intermittent than in the continuous exposure. The authors deduce that this latter finding makes it unlikely that the DNA damage, reflected in the alkaline comet assay, was due to increased temperature, since this would have been higher in the continuous exposure.

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