October 2006

Brain tumours and occupational exposure to RFR

This study was carried out by the German part of the international Interphone study. In this paper the authors investigated the association between radiofrequency/microwave (RF/MW) EMF occupational exposure and the risk of glioma or meningioma.

No significant relationship between occupational exposure to RF/MW EMF and brain tumours was found. There was a slight, though not statistically significant, increase in adjusted odds ratio with increasing duration of exposure, for both glioma and meningioma cases. However, these results were based on low number of cases.

For more, see "Research - Epidemiology".

Reference: Berg G, Spallek J, Schuz J, Schlefor B, et al. Occupational exposure to radio frequency/microwave radiation and the risk of brain tumours: Interphone study group, Germany. Am J Epidemiol 2006;164:538-548.

No effect of RFR on cultured brain cells

A recent study has found no evidence that exposure of glial cells to RFR at 900 MHz frequency and SARs of up to 27 W/kg led to cell damage. A variety of markers of cell damage were measured. Conversely, positive controls exposed to temperature increase, sometimes as little as 1ºC, showed marked evidence of cell damage. The authors comment: "This indicates the possibility that some studies showing microwave-radiation effects from mobile telephone signal strength levels might be the result of small temperature increases..."

For more, see "Research - Toxicological - brain function".

Reference: Thorlin T, Rouquette J-M, Hamnerius Y, Hansson E, et al. Exposure of cultured astroglial and microglial brain cells to 900 MHz microwave radiation. Radiat Res 2006;166:409-421.

Another animal study finds no evidence of RFR effect on tumour promotion

There have been numerous studies that have examined the effect of RFR on tumour initiation or promotion in animals. The vast majority of these have found no effect. Heikkinen and colleagues have added another to this list. They exposed rats to a combination of RFR and a known carcinogenic agent for up to 2 years, and found no evidence that RFR altered the outcome.

For more, see "Research - Toxicological - Cancer studies - Tumour growth and Development".

Reference: Heikkinen P, Huuskonen H, Komulainen H, Kumlin T, et al. No effects of radiofrequency radiation on 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone-induced tumorigenesis in female Wistar rats. Radiat Res 2006;166:397-408.


No breakdown of blood-brain barrier with RFR exposure

Finnie and colleagues previously examined vascular permeability changes in the fetal mouse brain after exposure to RFR. In the present paper they reported blood-brain barrier integrity in the neonatal brain after exposure to mobile telephony. The authors exposed newborn mice to a 60-minute far-field whole body exposure at 900 MHz, and SAR of 4 W/kg, on 7 successive days postnatally. No evidence of BBB breakdown was found in the exposed group.

For more, see "Research - Toxicological - brain function".

Reference: Finnie JW, Blumbergs PC, Cai Z, Manavis J, et al. Neonatal mouse exposure to mobile telephony and effect on blood-brain barrier. Pathology 2006;38:262-263.


Another study shows no genotoxic effect from RFR exposure

Numerous studies have examined the effect of RFR exposure on genotoxicity. Vijayalaxmi investigated the effects of exposure of cultured lymphocytes from human donors to 2.45 or 8.2 GHz RFR for 2 hours. There was no evidence of cytogenetic damage.

For more, see "Research - Toxicological - cancer studies".

Reference: Vijayalaxmi. Cytogenetics studies in human blood lymphocytes exposed in vitro to 2.45 GHz or 8.2 GHz radiofrequency radiation. Radiat Res 2006;166:532-538.


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