tumours and occupational exposure to RFR
No significant relationship between occupational exposure to RF/MW EMF and brain tumours was found. There was a slight, though not statistically significant, increase in adjusted odds ratio with increasing duration of exposure, for both glioma and meningioma cases. However, these results were based on low number of cases.
For more, see "Research - Epidemiology".
Berg G, Spallek J, Schuz J, Schlefor B, et al. Occupational exposure
to radio frequency/microwave radiation and the risk of brain tumours:
Interphone study group, Germany. Am J Epidemiol 2006;164:538-548.
A recent study has found no evidence that exposure of glial cells to RFR at 900 MHz frequency and SARs of up to 27 W/kg led to cell damage. A variety of markers of cell damage were measured. Conversely, positive controls exposed to temperature increase, sometimes as little as 1ºC, showed marked evidence of cell damage. The authors comment: "This indicates the possibility that some studies showing microwave-radiation effects from mobile telephone signal strength levels might be the result of small temperature increases..."
more, see "Research - Toxicological
- brain function".
There have been numerous studies that have examined the effect of RFR on tumour initiation or promotion in animals. The vast majority of these have found no effect. Heikkinen and colleagues have added another to this list. They exposed rats to a combination of RFR and a known carcinogenic agent for up to 2 years, and found no evidence that RFR altered the outcome.
Reference: Heikkinen P, Huuskonen H, Komulainen H, Kumlin T, et al. No effects of radiofrequency radiation on 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone-induced tumorigenesis in female Wistar rats. Radiat Res 2006;166:397-408.
Finnie and colleagues previously examined vascular permeability changes in the fetal mouse brain after exposure to RFR. In the present paper they reported blood-brain barrier integrity in the neonatal brain after exposure to mobile telephony. The authors exposed newborn mice to a 60-minute far-field whole body exposure at 900 MHz, and SAR of 4 W/kg, on 7 successive days postnatally. No evidence of BBB breakdown was found in the exposed group.
For more, see "Research - Toxicological - brain function".
Reference: Finnie JW, Blumbergs PC, Cai Z, Manavis J, et al. Neonatal mouse exposure to mobile telephony and effect on blood-brain barrier. Pathology 2006;38:262-263.
Numerous studies have examined the effect of RFR exposure on genotoxicity. Vijayalaxmi investigated the effects of exposure of cultured lymphocytes from human donors to 2.45 or 8.2 GHz RFR for 2 hours. There was no evidence of cytogenetic damage.
For more, see "Research - Toxicological - cancer studies".
Vijayalaxmi. Cytogenetics studies in human blood lymphocytes exposed
in vitro to 2.45 GHz or 8.2 GHz radiofrequency radiation. Radiat Res