of the heat shock response to RFR
we mentioned in the March '05 edition
of "What's New", the effect
of radiofrequency radiation (RFR) on the heat shock response is
unclear. In a recent article, Cotgreave reviews the evidence and
concludes that many of the studies "are flawed by inconsistencies
in exposure models, cell types used and the independent reproducibility
of the findings".
Cotgreave IA (2005): Biological stress responses to radio frequency
electromagnetic radiation: are mobile phones really so (heat) shocking?
Arch Biochem Biophys 435:227-40.
tumour in cell phone users in urban and rural areas
and associates have published another paper based on the case-control
study they carried out in Sweden from 1997 to 2000. On this occasion
they have re-analyzed their data to examine whether rural users
of cell phones have a higher risk of brain tumour than urban users.
The output power level from cell phones may be higher in rural areas
because of the greater distance between base stations. The authors
report that for digital phone users with more than 5 years latency
time between first use of the phone and diagnosis of a tumour, the
odds ratio was 3.2. The
authors state, however, that their results should be interpreted
with caution, because of the low numbers of cases in some of their
For more, see "Research-Epidemiology".
Hardell L, Carlberg M, Mild KH (2005): Use of cellular telephones
and brain tumour risk in urban and rural areas. Occup Environ Med
The effects on the ear of EMFs from mobile phones
recent publications have addressed the question of whether exposure
to electromagnetic fields (EMFs) from mobile phones affect the functioning
of the human ear.
and colleagues from Lithuania found that short-term exposure (10
minutes) had no effect on the hearing of 30 young adult volunteers.
Oysu et al. from Istanbul reported no adverse effect on auditory
brainstem responses from 15 minutes exposure. A German team found
no effect on either hearing or vestibular (balance) functions.
more, see "Research - Clinical
Experiments - Others - Hearing".
Uloziene I, Uloza V, Gradauskiene E, Saferis V. Assessment of potential
effects of the electromagnetic fields of mobile phones on hearing.
BMC Public Health 2005;5:39
C, Topak M, Celik O, Yilmaz HB, et al. Effects of the acute exposure
to the electromagnetic field of mobile phones on human auditory
brainstem responses. Eur Arch Otorhinolaryngol 2005 Feb 25 (Epub
ahead of print).
HW, Sievert U, Eggert S, Wild W. Can electromagnetic fields emitted
by mobile phones stimulate the vestibular organ? Otolaryngol Head
Neck Surg 2005;132:43-9.
U, Eggert S, Pau HW. Can mobile phone emissions affect auditory
functions of cochlea or brain stem? Otolaryngol Head Neck Surg 2005;132:451-5.
Correspondence on Swedish brain tumour
the October '04 issue of "What's
New" we mentioned the study of Lonn and colleagues that
reported an association between long-term use of cell phones and
In the May publication of the journal "Epidemiology" there
are five letters discussing various aspects of the study. Some of
the authors previously published articles on this subject.
Mobile phone use and acoustic neuromas. Epidemiology, May 2005:414-418.
Authors: Tarone RE and Inskip PD; Stang A, Schmidt-Pokrzywniak A,
Jockel K-H; Hardell L, Mild KH; Thomas BN, Flowers D, Caswell J,
Robbe IJ; Johnston SA, Scherb H.
and skin damage in rats - prevention by melatonin
and colleagues reported that exposure to 900 MHz RFR for 30 minutes
a day for 10 days led to increased fibrosis in exposed rats' skins,
and that this effect was likely due to oxidative stress. Melatonin
administered for 10 days orally prior to the radiation reduced the
fibrosis. There are no details, however, of the temperatures induced
by the radiation.
more, see "Research - Toxicological
experiments - others - free oxygen radicals".
Ayata A, Mollaoglu H, Yilmaz HR, Akturk O, et al. Oxidative stress-mediated
skin damage in an experimental mobile phone model can be prevented
melatonin. J Dermatol 2004;31:878-883.
study suggests RFR can cause brain changes in rats
authors studied the effects of RFR on the biochemistry and microscopic
anatomy of the rat's brain. They used a heads-only exposure system
for 15 minutes, and the RFR was emitted at 900 MHz frequency with
pulse modulation. The SAR was 6 W/kg. They found significant changes
in chemicals involved in various neurotransmission systems, and
observed a strong glial reaction (suggesting damage to nerve cells)
authors do not believe that the results noted are due to thermal
effects, but base this on experiments on a gel phantom and not on
direct measurement. They state that their experiments should be
repeated at lower power e.g. 2W/kg.
Mausset-Bonnefont AL, Hirbec H, Bonnefont X, Privat A, et al. Acute
exposure to GSM-900 MHz electromagnetic fields induces glial reactivity
and biochemical modifications in the rat brain. Neurobiol Dis 2004;17:445-454.