Design of new study on melanoma of the eye
A recent article outlined the design of a study of uveal melanoma (a tumour of the iris and related structures in the eye). Exposure to radiofrequency radiation from cell phones is one of the main areas to be explored, but a variety of potential risk factors will be included. The study compares newly diagnosed cases of the tumour in Germany with controls. The latter are of three types. Population-based controls are randomly selected from population lists, and will be matched to the cases for age, gender, and residential area. A second group will be drawn from the clients of ophthalmologists who have referred cases to the study. A third group will be siblings of cases. Data will be collected by self-administered questionnaire and by telephone interview. The authors hope to publish the study results in the summer of 2005.
The impetus for the research study was the publication of another German study on uveal melanoma in 2001 (Stang and colleagues). Three of the authors of the present paper contributed to the earlier paper. The 2001 study was criticized on methodological grounds. For more, see "What's New" of February 2001, and "Research - Epidemiology".
Schmidt-Pokrzywniak A, Jockel KH, Bornfeld N, Stang A. Case-control
study on uveal melanoma (RIFA): rational and design. BMC Ophthalmol
Another review of
the epidemiology of health effects of exposure to radiofrequency radiation
has been published. The conclusions of the authors are similar to other
Ahlbom A, Green A, Kheifets L, Savitz D, Swerdlow A (2004): Epidemiology
of health effects of radiofrequency exposure. Environ Health Perspect
A group of German
researchers has published two papers describing studies in which they
assessed the validity of self-reported cell phone use, as documented
in a questionnaire used in the INTERPHONE study (see "Research
Programs - IARC).
Berg G, Blettner M. Validation of self-reported cellular phone use.
Journal of Exposure Analysis and Environmental Epidemiology 2004;14:245-248.