Cell phones and non-Hodgkin lymphoma
A US case-control study has examined the role of cell phone use in the occurrence of non-Hodgkin lymphoma (NHL). There were 551 cases (79% participation) and 462 controls (55% participation). There was little evidence of an increased risk of NHL with use of cell phones. One non-statistically significant increased odds ratio was seen in men who used cell phones for 6 years or more, but this was based on 7 cases, there was no dose-response trend, and there was no similar result in women. The authors suggested that this was likely to be a chance finding.
For more, see "Research - Epidemiology".
Linet MS, Taggart T, Severson RK, Cerham JR, et al. Cellular telephones
and non-Hodgkin lymphoma. Int J Cancer 2006;119:2382-2388.
and colleagues exposed two types of human cells to RFR similar to that
used in the International Mobile Telecommunication 2000 (IMT-2000) cellular
system. They were exposed to W-CDMA radiation and CW radiation at SARs
up to 800 mW/kg for 48 hours. No significant differences were seen in
the percentage of apoptotic
cells that were RFR-exposed or sham-exposed, or in expression of phosphorylated
p53 gene or total p53.
Hirose H, Sakuma N, Kaji N, Suhara T, et al. Phosphorylation and gene
recent studies have examined the effect of exposure to RFR on the production
of oxidative stress in rats. Yurekli and colleagues simulated far-field
exposure from base stations, and found significant changes in blood
levels of markers of oxidative stress.
For more, see "Research - Toxicological - others- Free oxygen radicals".
References: Yurekli AI, Ozkan M, Kalkan T, Saybasili H, et al. GSM base station electromagnetic radiation and oxidative stress in rats. Electromagnetic Biology and Medicine 2006;25:177-188.
AR, Bonatto F, Pasquali MA, Polydoro M, et al. Oxidative stress effects
on the central nervous system of rats after acute exposure to ultra
high frequency electromagnetic fields. Bioelectromagnetics 2006;27:487-493.
and colleagues from Montreal, Canada, used the technique of proton magnetic
resonance spectroscopy (MRS) that, they claimed, had never been used
before to study the possible effects of cell phones on brain function.
MRS allows the non-invasive examination of the brain by measuring the
levels of certain metabolites that reflect the condition of neurons
and glial cells, as well as membrane metabolism and energy status.
For more, see “Research - Clinical - cognitive function”.
Khiat A, Boulanger Y, Breton G. Monitoring the effect of mobile phone
use on the brain by proton magnetic resonance spectroscopy. International
Journal of Radiation Biology 2006;82:681-685.
Nam and colleagues from Korea have reported a study of 21 teenagers and 21 adults who were RFR- or sham-exposed. The RFR was from a CDMA phone (835 MHz, SAR 1.6 W/g). The exposure was 30 minutes. There were no differences in pulse or respiratory rates or in blood pressure between the RFR and sham exposures in the teenagers, the adults or between the combined male and female groups. However, skin resistance, caused by increased sweat secretion, was decreased in the teenagers, and in the combined male group, when exposed to RFR. The study was double blind, but can be criticized for the lack of randomization of the sequence of exposure. The sham exposure was always first.
For more, see “Research - Clinical – cardiovascular effects”.
Nam KC, Kim SW, Kim SC, Kim DW. Effects of RF exposure of teenagers
and adults by CDMA cellular phones. Bioelectromagnetics 2006;27:509-514.