August 2005

Another heat shock response study

Miyakoshi and colleagues have added to the growing list of publications on the effect of RF radiation on heat shock proteins. They found that exposure to 1.95 GHz frequency for up to 2 hours at SARs of 1, 2, and 10 W/kg did not affect the growth of human glioma cells, or the production of Hsp27 and Hsp70. They did find reduced phosphorylation of Hsp27 at 10 W/kg, but not at 1 or 2 W/kg.

For more, see "Research - Toxicological Experiments - Others - Heat shock response".

Reference: Miyakoshi J, Takemasa K, Takashima Y, Ding G-R, et al. Effects of exposure to 1950 MHz radio frequency field on expression of Hsp70 and Hsp27 in human glioma cells. Bioelectromagnetics 2005;26:251-257.

Review of acoustic neuroma

The March edition of "Radio Science Bulletin" contains a review by James Lin on acoustic neuroma. He discusses in detail the paper by Lonn and colleagues, which was part of the INTERPHONE study, and briefly reviews other publications on the subject.

For more on this topic, see "Research - Epidemiology".

Reference: Lin JC (2005). Mobile phone use and benign tumors of the auditory nerve. Radio Science Bulletin No 312 (March, 2005). www.ursi.org

Genotoxicity and RFR exposure

The issue of whether or not radiofrequency radiation (RFR) at cell phone frequencies can produce DNA breakage in exposed tissues has been debated since the mid-1990s. Lai and Singh (1995, 1996) reported that rats exposed for 2 hours to RFR at 2450 MHz and SARs of 0.6 and 1.2 W/kg, had increased DNA breaks in their brain cells. Others have failed to reproduce these findings. Diem and colleagues have now reported DNA breakage in human cells and rat tumour cells after 16 hours exposure to 1800 MHz at SAR of 2 W/kg. They found more effect with intermittent exposure than continuous, and argue that this supports the conclusion that the observed effects are non-thermal.

For more, see Research - Toxicological experiments - Cancer".

Reference: Diem E, Schwarz C, Adlkofer F, Jahn O, et al. Non-thermal DNA breakage by mobile-phone radiation (1800 MHz) in human fibroblasts and in transformed GFSH-R17 rat granulosa cells in vitro. Mutat Res 2005;583:178-183.

Another genotoxicity study shows no RFR effect

As mentioned above, there have been a number of studies assessing whether radiofrequency radiation (RFR) has a genotoxic effect on cells. Most have failed to find an effect. Another study has produced similar results. An Italian group that has been involved in genotoxic research for many years exposed cells to 900 MHz RFR for 2 hours. There was no evidence of DNA damage or alteration of cell proliferation.

For more, see "Research - Toxicological experiments - Cancer".

Reference: Zeni O, Romano M, Perotta A, Lioi MB, et al. Evaluation of genotoxic effects in human peripheral blood leukocytes following an acute in vitro exposure to 900 MHz radiofrequency fields. Bioelectromagnetics 2005;26:258-265.

Cell phone RFR and allergy tests

A recent report suggests that exposure to RFR from a cell phone for 30 minutes can lead to changes in allergy blood tests in patients with atopic eczema dermatitis syndrome. The report does not offer any explanation for a mechanism that might produce this effect.

For more, see "Research - Clinical Experiments - Others - Immune system".

Reference: Kimata H. Microwave radiation from cellular phones increases allergen-specific IgE production. Allergy 2005;60:838-9

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