Autores
Hardell L, Carlberg M, Mild KH (2005b)

Hardell and colleagues have previously presented results of two case-control studies of the risk of brain tumours in users of cell phones. The current paper reports on a third study. The cases were patients with brain tumour recruited during July 1, 2000, and December 31, 2003. They were residents of two medical regions in Sweden - Uppsala/Orebro and Linkoping. All had a histopathological diagnosis reported to the cancer registries. Controls were from the same region and were matched for age and sex. A questionnaire was sent to the participants and the answers supplemented by a phone call with a trained interviewer. The year of diagnosis of a case was used for the corresponding control in analyses using time of use of a phone. Attempts were made to ascertain type of phone used, and the ear used during a phone call. Although cases were matched with controls, matched-pair analyses were not used. A large number of statistical results are presented, but there is no evidence that adjustments were made for multiple analyses.

The results are restricted to cases of benign brain tumour. A total of 413 cases were included (89% participation). These included 84 cases of acoustic neuroma and 305 cases of meningioma. Another 24 cases of other types of benign tumour were not included in the analysis. Although a large number of results are given, only one table shows results for a multivariate analysis, in which adjustment has been made for age, sex, socioeconomic index, and year of diagnosis. For acoustic neuroma, the Odds Ratio (OR) for use of an analogue phone, based on 20 cases, was 2.1 (95% CI = 1.1-3.8). There was no evidence of a dose-response effect, but the numbers of cases in different latency groups are small. For digital phones, the OR was 1.4 (CI 0.8-2.4). For meningioma, none of the results of the multivariate analysis was significant.


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